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马海龙
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上海交通大学医学院附属第九人民医院 | 口腔科
个人简历
基本信息:                                                                    
    名:马海龙               别:
    族:汉族                 贯:湖北十堰
政治面貌:中共党员         出生年月:1988年8月
    业:口腔颌面头颈肿瘤     历:博士研究生
毕业学校:上海交通大学     毕业时间:2018年06月
联系电话:188****1609      外语水平:英语六级
电子邮箱:mah****l21@163.com   :四级(网络工程师)
教育经历:                                               
2015年-2018年,上海交通大学医学院附属第九人民医院(博士),
2012年-2015年,上海交通大学医学院附属第九人民医院(硕士),
               
2007年-2012年,华中科技大学(本科)
实习工作经历:                                                 
2018年7月至今,上海交通大学医学院附属第九人民医院住院医师规范化培训(口腔颌面-头颈肿瘤科基地)
2017年01月-2018年1月,上海第九人民医院口腔颌面-头颈肿瘤科
2014年07月-2014年12月,上海第九人民医院口腔颌面-头颈肿瘤科
科研工作 :(国自然青年基金及上海市人才计划各1项)                                               
国家自然科学基金青年项目,81902747,干扰素α通过LncRNA-MX1-215促进PD-L1表达调控头颈鳞癌免疫抑制的机制研究,2020.01-2022.12,21万元,在研,主持。
上海市青年科技英才扬帆计划,19YF1427000,m6A甲基化在干扰素α诱导头颈鳞癌PD-L1表达中的作用及机制研究,2019.05-2022.04, 20万元,在研,主持
上海交通大学医学院“博士创新基金”,BXJ201728,stathmin在口腔鳞癌中高表达促进TPF诱导化疗耐药的机制研究,2017.04-2018.04,2万元,已结题,主持
以第一作者及通讯作者发表SCI论著17篇,影响因子>15的2篇,影响因子>5的7篇,总影响因子92.731

 附件材料:主要科研成果
Ma HL, Chang HY, Yang WY, Lu YS, Hu JZ, Jin SF. A novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma. Mol Cancer, 2020, 19(4). (第一作者,IF=15.302).
Qiaoshi Xu,Hailong Ma*, Hanyue Chang, Zhien Feng, Chenping Zhang*, Xi Yang*. The interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway. Cell death &disease, 2020, 11:405. (通讯作者, IF=6.304
Wu-tong Ju#, Hai-long Ma#, Tong-Chao Zhao#, Si-yuan Liang, Dong-wang Zhu, Li-zhen Wang, Jiang Li, Zhi-yuan Zhang, Ge Zhou, Lai-ping Zhong. Stathmin guides personalized therapy in oral squamous cell carcinoma. Cancer science 2020;00:1–11 (共同第一作者,IF=4.966).
Jiayi Li, Chaoji Shi, Rong Zhou, Yong Han, Shengming Xu, Hailong Ma*, Zhiyuan Zhang*. The crosstalk between AXL and YAP promotes tumor progression through STAT3 activation in head and neck squamous cell carcinoma. Cancer science, doi:10.1111/cas.14546 (通讯作者, IF=4.966)
Jin SF, Yang X, Li JY, Yang WY, Ma HL*, Zhang ZY*. p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma. Mol Cancer, 2019,18(1):38. (通讯作者, IF=15.302
Yang WY, Jiang CL, Xia W, Ju HY, Jin SF, Liu SL, Zhang LM, Ren GX, Ma HL*, Ruan M*, Hu JZ*. Blocking autophagy flux promotes interferon-alpha-mediated apoptosis in head and neck squamous cell carcinoma. Cancer letters. 2019,451:34-47. (通讯作者, IF=7.36
Ma HL, Yang WY, Zhang LM, Liu SL, Zhao M, Zhou G, Wang LZ, Jin SF, Zhang ZY, and Hu JZ Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signaling in head and neck squamous cell carcinoma. Br J Cancer. 2019;120(3):317-330. (第一作者,IF= 5.791)
Ma HL, Jin SF, Yang WY, Zhou G, Zhao M, Fang SJ, Zhang ZY, Hu JZ. Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma. Br J Cancer, 2018,118(4):509-521. (第一作者,IF= 5.416)
Ma HL, Jin SF, Ju WT, Fu Y, Tu YY, Wang LZ, Jiang L, Zhang ZY, and Zhong LP. Stathmin is overexpressed and regulated by mutant p53 in oral squamous cell carcinoma. J Exp Clin Cancer Res. 2017;36:109. (第一作者,IF= 6.217)
Ma HL, Jin SF, Yang WY, Tian ZW, Liu SL, Wang Y, Zhou G, Zhao M, Gvetadze S, Zhang ZY, and Hu JZ. Interferon-alpha Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma. J Cancer. 2017;8:2384-2393. (第一作者,IF = 3.249)
Ma HL, Jin SF, Du Z, Wang LZ, Zhang ZY, Wang Y. Pathology and management of masses in the accessory parotid gland region: 24-year experience at a single institution. J Craniomaxillofac Surg, 2018,46(2):183-189. (第一作者,IF = 1.942)
Ma HL, Jin SF, Tao WJ, Zhang ML, Zhang ZY. Overexpression of stathmin/oncoprotein 18 correlates with poorer prognosis and interacts with p53 in oral squamous cell carcinoma. J Craniomaxillofac Surg. 2016;44:1725-1732. (第一作者,IF =1.583)
Ma HL, Yu C, Liu Y, Tan YR, Qiao JK, Yang X, Wang LZ, Li J, Chen Q, Chen FX, Zhang ZY, and Zhong LP Decreased expression of glutathione S-transferase pi correlates with poorly differentiated grade in patients with oral squamous cell carcinoma. J Oral Pathol Med. 2015;44:193-200. (第一作者,IF =1.859)
Qiaoshi Xu, Hanyue Chang, Xuerui Tian1, Chao Lou, Hailong Ma, Xi Yang. Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma. J Cancer. 2020; 11(6): 1596-1605. (通讯作者, IF=3.565
Jin SF#, Ma HL#, Yang WY, Ju HY, Wang LZ, Zhang ZY. Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1. J Mol Med (Berl), 2018,96(6):513-525. (共同第一作者,IF=4.746)
Jin SF#, Ma HL#, Liu ZL, Fu ST, Zhang CP, He Y. XL413, a cell division cycle 7 kinase inhibitor enhanced the anti-fibrotic effect of pirfenidone on TGF-beta1-stimulated C3H10T1/2 cells via Smad2/4. Exp Cell Res, 2015,339(2):289-299. (共同第一作者,IF=3.378)
Xu X, Ma HL*, Jin SF*. One-Stage Treatment of Giant Condylar Osteoma: Alloplastic Total Temporomandibular Joint Replacement Aided by Digital Templates. J Craniofac Surg, 2018,29(3):636-639. (通讯作者, IF=0.785
朱黎林,杨文艺,马海龙*,胡镜宙*。IFNAR1在口腔鳞状细胞癌中的表达及意义。中国口腔颌面外科杂志 2017(15);240-244. (共同通讯作者)
马海龙,钟来平,张志愿。血管内皮细胞生长因子在口腔鳞状细胞癌进展和预后的作用研究进展,中国口腔颌面外科杂志 2014(12),175-178. (第一作者)
马海龙,钟来平,张志愿。头颈部鳞状细胞癌中肿瘤干细胞标志物的研究进展,临床口腔医学杂志 2013(29);377-379.(第一作者)
 
 

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日期 时间 会场 Session 角色 讲题
2022-04-16 16:00-16:10 口腔颌面肿瘤整合专场

口腔颌面肿瘤整合医学专委会分会场-第八单元 青年医师课题展示

讲者 干扰素α在头颈鳞癌免疫调节中的作用的和机制研究